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Information in English

Arthrogryposis multiplex congenita, or short AMC, is a condition of stiff joints from birth on which in most cases affects multiple joints. It is a specific form of a physical handicap. AMC is not cureable, but it is not progressive.

What is Arthrogryposis (AMC)?

By Arthrogryposis multiplex congenita (AMC) is understood a state of stiff joints from birth on. This stiffness can be limited to some joints; but also multiple, in extreme cases, even all joints can be affected. Nerves, muscles, tendons and most of all the joint capsules are affected.

The term AMC describes a clinical picture that can be extremely variable.

The causes of AMC are mostly resulting from disorders in the infantile development during pregnancy that takes place approximately in weeks 8 to 11 of pregnancy and is characterized by a neurological aberration. Consequently the results are a disturbed development of the muscles (connective tissue, hypoplasia, non-development) which constricts the development appropriate to function of the joints. In rare cases there are also genetic causes.


Highest priority for therapy is the desired function; anatomical-aesthetical considerations have to be subordinated. The child shouldbe assisted to undergo, as far as possible, a regular development according to its age. Each method of therapy has to consider the psychical condition of the child. Too much of therapy can be as harmful as too little.

Physiotherapy and occupational therapy

Important therapeutical success can be achieved by physiotherapy and occupational therapy. Treatment should be started as soon as possible.

By manual therapy stiffened joints can be loosened step by step. Additionaly treatments of neurological basis (e.g. concepts of Vojta and Bobath) are being undertaken that stimulate the neuromuscular activities, if present.

The intensity of therapy is especially great in the first years. Later it can be reduced without considerable advantages. A basic program should secure the established success in long-term.

Orthopedic aids

Despite a lot of physiotherapy not all children can be enabled to walk. Then additional measures have to be undertaken. These are the use of orthopedic aids such as splints and/or supporting appatuses or even surgery.

After surgical corrections the result achived can be stabilized by splints. Children with very weak muscles can learn to walk with lightweight splints. Redressing splints are not suitable to correct defective joint positions.


Surgery needs to be considered,


Defective positions shall be corrected or eliminated to an extend that the child can use its weak muscles according to function.

Supreme objective of all orthopedic treatment and surgery is to improve the function of the joints and to enable the child to lead a life as autonomous and independent as possible.

Interessengemeinschaft Arthrogryposis e.V.

The Interessengemeinschaft Arthrogryposis (IGA) e.V. – Community of Interest for Arthrogryposis – was founded in March 1992. Its mission is to be the lobby of all those concerned with AMC in the German-speaking countries.

Our mission:

Our activities:

All this needs active members and costs money. That’s why we need your support. Everyone can become a member – as an affected person or as a supporting member. The association exclusively and directly pursues non-profit and charitable purposes of public utility. Donations are always welcome.

Regional Contacts

The Interessengemeinschaft Arthrogryposis e.V. has network of regional contacts all over Germany, Austria and Switzerland. The latest list of contact persons can be found at www.arthrogryposis.de on the Internet.

Contact person for international inquiries:

Johannes Borgwardt
D-10405 Berlin
Phone +49 30 92124301

Please also visit our forum in English.


Dr. med. Johannes Correll
Orthopädie am Marienplatz
Weinstraße 3, D-80333 München
Phone +49 89 242944-0, Fax +49 89 29160815

Interessengemeinschaft Arthrogryposis e.V.
Incorportated at the German district court Bad Säckingen, VR 537